Neonatal-Onset Multisystem Inflammatory Disease (NOMID), also known as Chronic Infantile Neurological Cutaneous Articular Syndrome (CINCA), is a type of autoinflammatory disease. NOMID affects newborn children of both sexes and all races. It is very rare, with an estimate of less than 1 case per 1,000,000 people.
1 of 3 Autoinflammatory Diseases Called CAPS
NOMID is the most severe form of the Cryopyrin-Associated Periodic Syndromes (CAPS). These conditions are grouped together because they share common symptoms that can flare up frequently and vary from person to person. The conditions also differ in how severe the inflammation can become and the parts of the body affected:
Fever Joint pain/swelling
Eye redness/pain Headaches
Range of inflammation in Caps
Patients with NOMID experience symptoms more severely. Some are constant, especially the rash and fever most babies get at birth or in the weeks after. Infections and physical and mental stress can also trigger inflammation flares.
NOMID is more severe than other forms of CAPS because inflammation causes additional symptoms and damage that progress over time. These may slow the baby’s growth and lead to physical and mental disability. The organs and areas of the body that can be affected include the brain and the central nervous system, bones, joints and muscles, eyes, and ears, among others
Unfortunately, NOMID is a lifelong condition. Those who are not treated or cannot control their symptoms while on treatment are at risk for the most harmful complications.
Kineret® Helps Reduce
Patients in studies reported significant improvment with Kineret
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A NOMID Journey: Quinn
Learn about one child's diagnosisand how the family manages their symptoms