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Neonatal-Onset Multisystem Inflammatory Disease (NOMID), also known as Chronic Infantile Neurological Cutaneous Articular Syndrome (CINCA), is a type of autoinflammatory disease. NOMID affects newborn children of both sexes and all races. It is very rare, with an estimate of less than 1 case per 1,000,000 people.

1 of 3 Autoinflammatory Diseases Called CAPS

NOMID is the most severe form of the Cryopyrin-Associated Periodic Syndromes (CAPS). These conditions are grouped together because they share common symptoms that can flare up frequently and vary from person to person. The conditions also differ in how severe the inflammation can become and the parts of the body affected:

Hive-like rash
Joint pain/swelling
Eye redness/pain

Range of inflammation in Caps

Patients with NOMID experience symptoms more severely. Some are constant, especially the rash and fever most babies get at birth or in the weeks after. Infections and physical and mental stress can also trigger inflammation flares.

NOMID is more severe than other forms of CAPS because inflammation causes additional symptoms and damage that progress over time. These may slow the baby’s growth and lead to physical and mental disability. The organs and areas of the body that can be affected include the brain and the central nervous system, bones, joints and muscles, eyes, and ears, among others

Unfortunately, NOMID is a lifelong condition. Those who are not treated or cannot control their symptoms while on treatment are at risk for the most harmful complications.

Kineret® Helps Reduce
NOMID Symptoms

Patients in studies reported significant improvment with Kineret

More About Kineret Results

A NOMID Journey: Quinn

Learn about one child's diagnosisand how the family manages their symptoms

Watch Quinn's Story


Kineret® is a prescription medicine called an interleukin-1 receptor antagonist (IL-1ra) used to:

Kineret is not for children with Juvenile Rheumatoid Arthritis


Do not take Kineret if you are allergic to:

Before you use Kineret, tell your healthcare provider if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.Kineret and other medicines may affect each other and cause serious side effects. Especially tell your healthcare provider if you take certain other medicines that affect your immune system called Tumor Necrosis Factor (TNF) Blockers. Ask your healthcare provider for a list of these medicines if you are not sure.

Kineret may cause serious side effects, including:

The most common side effects of Kineret for RA include: 


The most common side effects of Kineret for NOMID include:

Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all of the possible side effects of Kineret. For more information ask your healthcare provider or pharmacist.

Please see full Prescribing Information