This information is intended for US healthcare professionals. If you are a healthcare professional, click “I Agree” to continue.

Kineret is given as a daily subcutaneous injection (an injection under the skin). Kineret comes in a pre-filled graduated syringe. It can be injected by a caregiver or self-injected by patients who are physically and emotionally capable. It is important to receive appropriate instructions from your healthcare provider on the correct dose of Kineret to give, how to inject, and the proper way to dispose of used syringes.

Kineret Packs

  • Available in 7- or 28-day packs with prefilled graduated syringes
  • Keep original pack refrigerated at 36°to 46°F (2° to 8°C) and keep at the
    correct tempertature when you travel
  • Never freeze or shake Kineret and keep away from light
  • Safely dispose of Kineret that is out of date or no longer needed
  • Keep out of the reach of children

Graduated Syringe

  • Each contains 100 mg of Kineret
  • Each syringe is marked in 20 mg increments to help with dosing accuracy
  • For doses less than 100 mg, adjust the syringe to the needed amount of medicine
  • For doses above 100 mg, use 2 syringes and adjust 2nd syringe as needed

An attachable syringe grip is also available to help keep the syringe stable during injection. Ask your pharmacist for product recommendations.


Kineret® is a prescription medicine called an interleukin-1 receptor antagonist (IL-1ra) used to:

Kineret is not for children with Juvenile Rheumatoid Arthritis


Do not take Kineret if you are allergic to:

Before you use Kineret, tell your healthcare provider if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.Kineret and other medicines may affect each other and cause serious side effects. Especially tell your healthcare provider if you take certain other medicines that affect your immune system called Tumor Necrosis Factor (TNF) Blockers. Ask your healthcare provider for a list of these medicines if you are not sure.

Kineret may cause serious side effects, including:

The most common side effects of Kineret for RA include: 


The most common side effects of Kineret for NOMID include:

Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all of the possible side effects of Kineret. For more information ask your healthcare provider or pharmacist.

Please see full Prescribing Information