Full Prescribing Information and Instructions for Use
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Kineret for NOMID Patient Stories Using Kineret KINERET® On TRACK Resources Kineret for RA Patient Stories Using Kineret KINERET® On TRACK Resources

Meet Quinn and her mother, Colleen.


Quinn had signs of NOMID from birth.

"No one at the hospital—not even the chief neonatologist—had ever seen anything like Quinn’s constellation of symptoms."—Colleen, Quinn's mother

Each NOMID patient’s path to diagnosis is unique—and like most, Quinn's was complex.

"During the first 6 months of Quinn’s life, we were referred to specialist after specialist—12, to be exact. She underwent countless tests and tried various forms of treatment with no relief."—Colleen, Quinn's mother

When your child is seriously ill, obtaining a diagnosis can be a relief.

"At this point, however, there was nothing we wouldn’t have tried if it meant there was even a possibility it would help our daughter."—Colleen, Quinn's mother

In Quinn’s case, Kineret reduced the signs and symptoms of NOMID.

"It was a turning point in a year of suffering: Quinn’s NOMID diagnosis had led us to the treatment that might be right for her."—Colleen, Quinn's mother

Injecting Kineret is now part of Quinn’s daily routine.

"I’m not gonna lie. For a long time, she put up a fight about it almost every time, but, hey, she’s a kid! That's kind of her job, right? She doesn’t fight it so much anymore; she understands that she needs her injections. If for some reason our routine is off or we’re running late, she’s the first one to remind me: 'Mommy, you forgot my Kineret.'"—Colleen, Quinn's mother

INDICATIONS

Kineret® is a prescription medicine called an interleukin-1 receptor antagonist (IL-1ra) used to:

  • Reduce the signs and symptoms, and slow the damage of moderate to severe active rheumatoid arthritis (RA) in people age 18 years and older when 1 or more other drugs for RA have not worked
  • Treat people with a form of Cryopyrin-Associated Periodic Syndromes (CAPS) called Neonatal-Onset Multisystem Inflammatory Disease (NOMID)

IMPORTANT SAFETY INFORMATION

Who should not take Kineret?

People who are allergic to:

  • proteins made from bacteria called E. coli. Ask your healthcare provider if you are not sure
  • anakinra or any of the ingredients in Kineret. See the end of the patient leaflet for a complete list of ingredients in Kineret

What information should I know before starting Kineret?

Before you use Kineret, tell your healthcare provider if you:

  • have an infection, a history of infections that keep coming back, or other problems that can increase your risk of infections
  • have kidney problem
  • are scheduled to receive any vaccines. People using Kineret should not receive live vaccines
  • are pregnant or plan to become pregnant. It is not known if Kineret will harm your unborn baby
  • are breastfeeding or plan to breastfeed. It is not known if Kineret passes into your breast milk. You and your healthcare provider should decide if you will use Kineret or breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Kineret and other medicines may affect each other and cause serious side effects. Especially tell your healthcare provider if you take certain other medicines that affect your immune system called Tumor Necrosis Factor (TNF) Blockers. Ask your healthcare provider for a list of these medicines if you are not sure.

What are the possible side effects of Kineret?

Kineret may cause serious side effects, including:

  • serious infections. Kineret may lower your ability to fight infections. During treatment with Kineret, call your healthcare provider right away if you get an infection, have any sign of an infection including a fever or chills, or have any open sores on your body. You may get an infection if you receive live vaccines while you use Kineret. You should not receive live vaccines while you use Kineret.
  • allergic reactions. Stop using Kineret and call your healthcare provider or get emergency help right away if you have any of these symptoms of an allergic reaction: swelling of your face, lips, mouth or tongue; trouble breathing; wheezing; severe itching; skin rash, redness, or swelling outside of the injections site area; dizziness or fainting; fast heartbeat or pounding in your chest (tachycardia); or sweating.
  • decreased ability of your body to fight infections (immunosuppression). It is not known if treatment with medicines that cause immunosuppression, like Kineret, affect your risk of getting cancer.
  • low white blood cell count (neutropenia). Kineret may cause you to have a lower number of certain white cells (neutrophils). Neutrophils are important in fighting infections. You should have blood tests before starting treatment with Kineret, then monthly for 3 months. After the first 3 months you should have your blood tested every 3 months for up to 1 year.

The most common side effects of Kineret for RA include:

  • Injection site skin reactions, including redness, swelling, bruising, itching, and stinging. Most injection site reactions are mild, happen early during treatment, and last about 14 to 28 days
  • rheumatoid arthritis (RA) gets worse with treatment
  • sore throat or runny nose
  • headache
  • nausea
  • diarrhea
  • sinus infection
  • joint pain
  • feeling like you have the flu
  • pain in your stomach area

The most common side effects of Kineret for NOMID include:

  • Injection site skin reactions, including redness, swelling, bruising, itching, and stinging. Most injection site reactions are mild, happen early during treatment, and last about 14 to 28 days. Injection site reactions have been observed less frequently in people with NOMID
  • headache
  • vomiting
  • diarrhea
  • joint pain
  • fever
  • feeling like you have the flu
  • sore throat or runny nose

Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all of the possible side effects of Kineret. For more information ask your healthcare provider or pharmacist.

Please see full Prescribing Information.