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Kineret® is a medicine that is prescribed by a doctor to help manage the pain
and swelling symptoms associated with moderate to severely active rheumatoid
arthritis (RA). It is a kind of medicine known as a biological response
modifier (BRM) and is usually prescribed after treatment with one or more
disease-modifying antirheumatic drugs (DMARDs) have failed to effectively
manage the signs and symptoms.
A specific protein called interleukin-1 (IL-1) is produced by the body when part of it becomes inflamed and the immune system responds. Because RA is an inflammatory disease, production of IL-1 along with other mediators can be increased. Too much IL-1 can lead to additional pain, swelling, and stiffness of the joints. Kineret® is a synthetic form of a protein that naturally occurs in the body called interleukin-1 receptor antagonist (IL-1Ra). Kineret® can help manage the excess levels of IL-1 in the body. Only the patient and doctor can determine how well Kineret® is working for each case of RA. The time it takes to see improvement in symptoms varies from person to person. In clinical studies, most patients saw their arthritis symptoms improve in about 12 weeks after starting Kineret® treatment. Kineret® is supplied in single-use, prefilled glass syringes. Each syringe contains 100 mg of the medication, and it should be stored in the refrigerator at 36° to 46°F. It should not be shaken, frozen, or exposed to sunlight for extended periods of time. During travel, it is crucial to store Kineret® at the correct temperature. A complimentary travel cooler can be obtained by calling 1-866-KINERET (1-866-546-3738). Kineret® is designed to be injected by the patient or caregiver every day. It is important to receive appropriate instruction from your health care provider. It is best if the injection occurs at the same time of day every day (every 24 hours). It is important not to use Kineret® if it has passed the expiration date printed on the carton. Each dose should be checked for discoloration or contamination (particles in the solution) before being used. Only one dose should be administered per day. If only a partial dose is administered, the unused portion should be discarded and a new dose should be injected the next day. The Kineret® needle cover contain latex. Patients allergic to latex should talk to their health care provider before using Kineret®. |
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RHEUMATOID ARTHRITIS KINERET® AND RHEUMATOID ARTHRITIS DIET & EXERCISE REIMBURSEMENT IMPORTANT PRODUCT SAFETY INFORMATION |
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