The KINERET logo and generic name (anakinra)

KINERET Support Program

Megan was diagnosed with RA in 2011 at age 31.

"Suddenly, halfway through my PhD program, I was blindsided by a sudden and unexpected illness: fever, rashes, pain that crept up every limb from the throbbing joints in my hand and feet and prevented me from doing the most basic of tasks."—Megan, RA patient

Woman heading to work

Before starting KINERET, Megan tried multiple RA treatments, all of which failed.

"I spent two years trying and failing multiple RA drugs, never knowing which drug might treat some symptoms but exacerbate others. […] I began to feel that my rheumatologist and I were firing shots into the air and hoping we hit something."—Megan, RA patient

Based on Megan's history of IL-1–driven inflammatory RA symptoms, her rheumatologist prescribed KINERET.

"Knowing my history of RA symptoms, my rheumatologist chose to start me on KINERET, and I will be forever grateful for her insight."—Megan, RA patient

Woman sitting outside writing in a journal

Megan responded well to KINERET and had a reduction in symptoms within the first 12 weeks.

"Compared to how I felt when I was diagnosed, and during the three years after, the change is heartening."—Megan, RA patient

Megan has worked closely with her doctor to manage injection site reactions.

"I've found letting the solution warm up, and injecting slowly in a relaxed position (for example, sitting up in bed) is the best way for me to manage them."—Megan, RA patient

Woman on the phone

Kineret ON TRACK® has supported Megan throughout her KINERET treatment.

"Kineret ON TRACK® allowed me to work with a case manager and get KINERET sent right to my office."—Megan, RA patient

IMPORTANT SAFETY INFORMATION

INDICATIONS

KINERET® (anakinra) is a prescription medicine called an interleukin-1 receptor antagonist (IL-1Ra) used to:

RA: Reduce the signs and symptoms and slow the damage of moderate to severe active rheumatoid arthritis (RA) in people aged 18 years and older when 1 or more other drugs for RA have not worked

NOMID: Treat people with a form of Cryopyrin-Associated Periodic Syndromes (CAPS) called Neonatal-Onset Multisystem Inflammatory Disease (NOMID)

DIRA: Treat people with Deficiency of Interleukin-1 Receptor Antagonist (DIRA)

KINERET is not for children with Juvenile Rheumatoid Arthritis.

IMPORTANT SAFETY INFORMATION

Do not take KINERET if you are allergic to:

  • Proteins made from bacteria called E. coli. Ask your healthcare provider if you are not sure
  • Anakinra or any of the ingredients in KINERET. See the end of the patient leaflet for a complete list of ingredients in KINERET

Before starting KINERET, tell your healthcare provider if you:

  • Have an infection, a history of infections that keep coming back, or other problems that can increase your risk of infections
  • Are scheduled to receive any vaccines. People using KINERET should not receive live vaccines
  • Have kidney problems
  • Are pregnant or plan to become pregnant. It is not known if KINERET will harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if KINERET passes into your breast milk. You and your healthcare provider should decide if you will use KINERET or breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

KINERET and other medicines may affect each other and cause serious side effects.

KINERET may cause serious side effects, including:

Serious infections. KINERET may lower your ability to fight infections. Call your healthcare provider right away if you get an infection, have any sign of an infection including a fever or chills, or have any open sores on your body. Due to the risk of infection, you should not receive live vaccines while you use KINERET.

Serious allergic reactions. Stop using KINERET, call your healthcare provider, and get emergency help right away if you have any of these symptoms of a serious allergic reaction: swelling of your face, lips, mouth, or tongue; trouble breathing; wheezing; severe itching; skin rash, redness, or swelling outside of the injection site area; dizziness or fainting; fast heartbeat or pounding in your chest (tachycardia); or sweating. People with DIRA may have an increased risk of allergic reactions, especially in the first several weeks.

Decreased ability of your body to fight infections (immunosuppression). It is not known if treatment with medicines that cause immunosuppression, like KINERET, affect your risk of getting cancer.

Amyloidosis. KINERET may cause a buildup of abnormal proteins called amyloids around the injection site (a hard lump under the skin). Avoid using the same site to inject KINERET by rotating to alternating areas of the body. Your doctor may monitor you for amyloidosis.

Low white blood cell count (neutropenia). KINERET may cause you to have a lower number of certain white blood cells (neutrophils). Neutrophils are important in fighting infections. Your doctor should do blood tests to check your white blood cell level before starting and during the first year of treatment with KINERET.

The most common side effects of KINERET include:

  • Injection site skin reactions. The symptoms of injection site skin reactions may include: redness, swelling, bruising, itching, and stinging
  • RA gets worse with treatment, if you already have RA
  • Headache
  • Nausea and vomiting
  • Diarrhea
  • Joint pain
  • Fever
  • Feeling like you have the flu
  • Sore throat or runny nose
  • Sinus infection
  • Pain in your stomach area

Tell your healthcare provider if you have any side effect that bothers you or does not go away.

These are not all of the possible side effects of KINERET. For more information ask your healthcare provider or pharmacist. You can also see the Full Prescribing Information for KINERET including Patient Information and Instructions for Use at https://www.kineretrx.com/pdf/Full-Prescribing-Information-English.pdf

To report suspected side effects, contact Sobi North America at 1-866-773-5274 or FDA at 1-800-FDA-1088.

These are not all of the possible side effects of KINERET. For more information ask your healthcare provider or pharmacist. You can also see the Full Prescribing Information for KINERET including Patient Information and Instructions for Use at https://www.kineretrx.com/pdf/Full-Prescribing-Information-English.pdf

To report suspected side effects, contact Sobi North America at 1-866-773-5274 or FDA at 1-800-FDA-1088.